| Autor: |
Badis Tlili, Ahlem Trifi, Asma Mehdi, Cyrine Abdennebi, Foued Daly, Sami Abdellatif, Yosr Touil, Salah Ben Lakhal |
| Rok vydání: |
2022 |
| Popis: |
Background While High Flow Nasal Cannula (HFNC) use increased in COVID-19 hypoxic patients, the optimal timing of mechanical ventilation in COVID-19 is uncertain. We sought to evaluate the ROX index ([SpO2/FIO2]/breathing frequency) capacity to predict weaning from high-flow nasal cannula (HFNC) in COVID-19. Methods We performed a single-center, retrospective, observational study of subjects with respiratory failure from COVID-19 managed with HFNC. The ROX index was calculated at H 12 from HNFC and applied to predict HFNC failure. Subjects managed with HFNC were divided into two groups. And HFNC failure was defined as endotracheal intubation and invasive ventilation necessity in the first five days from admission. Standard statistical comparisons and regression analyses were used to evaluate the ROX index performance in prediction of HFNC failure. Results 121 subjects with COVID-19 were managed with HFNC. 66 (55.5%) were successfully weaned from HFNC and 55 (45.5%) required intubation and mechanical ventilation. High mortality rates have been reported in the last group. Rox index |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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