ChemInform Abstract: Discovery of a Novel Series of Cyclic Urea as Potent CCR5 Antagonists

Autor:	Mark P. Edelstein, Pat Wheelan, Rob Ferris, Matt Tallant, Jung Ho Jun, Maosheng Duan, Wieslaw M. Kazmierski, Zhiping Xiong, Dan Todd
Rok vydání:	2012
Předmět:	chemistry.chemical_compound chemistry Series (mathematics) Urea virus diseases General Medicine Combinatorial chemistry
Zdroj:	ChemInform. 43
ISSN:	0931-7597
DOI:	10.1002/chin.201209148
Popis:	Design and practical syntheses of a novel class of cyclic urea-based CCR5-antagonists demonstrating high antiviral activities against HIV-1 infection in both HOS and PBL assays are described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1f9a0fb57b02781762ddefca6a5c8e28 https://doi.org/10.1002/chin.201209148 Zobrazit plný text záznamu Plný text