Renale Effekte von Clonidin bei kardiochirurgischen Patienten
| Autor: | P. J. Kulka, P. Wegermann, M. Tryba |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Renal damage business.industry Acute postoperative renal failure Renal function General Medicine urologic and male genital diseases Cardiac surgery Structural Biology Internal medicine Anesthesia medicine Catecholamine Cardiology Radiology Nuclear Medicine and imaging In patient business Molecular Biology Sympathetic tone medicine.drug Angiology |
| Zdroj: | Clinical Research in Cardiology Supplements. 2:S85-S90 |
| ISSN: | 1861-0714 1861-0706 |
| DOI: | 10.1007/s11789-006-0044-7 |
| Popis: | Renal function is responsible for homoestasis in the organism. Renal impairment causes life-threatening damage. Intraoperative bleeding, hypotension, stress and toxins (endogenous, exogenous) during surgery could impair renal function and cause postoperative renal damage Mortality after coronary graft sur gery is usually between 1-2% anc acute postoperative renal failure (ARF) increases mortality up to 60-75%. High sympathetic tone and extracorporal circulation under coronary graft surgery are important factors influencing postoperative renal failure. Experimental and clinical studies have shown a reduction of sympathetic tone and catecholamine concentration by a 2 -agonists. Renal perfusion and glomerular filtration is improved. This could prevent renal damage in patients undergoing coronary graft surgery and extracorporal circulation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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