SYNTHETIC LACTOFERRIN IN DENTAL DISEASES PREVENTION AND TREATMENT: CURRENT TRENDS AND PERSPECTIVES
| Autor: | Yuriy Olegovich Paramonov, A Yu Turkina, A. V Shirokova |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
030106 microbiology Energy Engineering and Power Technology medicine.disease_cause Virus Microbiology 03 medical and health sciences fluids and secretions medicine Candida albicans chemistry.chemical_classification Innate immune system biology Lactoferrin business.industry General Engineering food and beverages Hepatitis B biology.organism_classification medicine.disease stomatognathic diseases 030104 developmental biology Herpes simplex virus chemistry Transferrin biology.protein Glycoprotein business |
| Zdroj: | Russian Journal of Dentistry. 23:84-90 |
| ISSN: | 2413-2934 1728-2802 |
| Popis: | The current trend in dental science is to develop novel approaches to the treatment of dental diseases. More often the body’s own proteins are being used, as well as lactoferrin that is the component of exocrine glands secretions. At present lactoferrin can be obtained biotechnologically. Lactoferrin is one of the innate immune system components and is a multifunctional glycoprotein from the transferrin family. This protein is capable of iron binding and thus deprives the microbiota of essential microelement. It’s efficacy against Str. mutans, A. actinomycetemcomitans, P. Gingivalis, P. Intermedia, Candida albicans was demonstrated. Lactoferrin is active against cytomegalovirus, herpes simplex virus, human immunodeficiency virus, hepatitis B and C virus. Immunomodulatory possibilities of lactoferrin have been shown. In dentistry recombinant lactoferrin is successfully applied in treatment of periodontal diseases, oral mucosa lesions of bacterial, viral and fungal etiology and also in dental caries prevention. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|