α-Keto Acids as Acylating Agents in the Synthesis of 2-Substituted Benzothiazoles and Benzoselenazoles

Autor:	Filipe Penteado, David B. Lima, Marcelo M. Vieira, Gelson Perin, Diego Alves, Claudio Santi, Eder J. Lenardão
Rok vydání:	2017
Předmět:	Reaction conditions 010405 organic chemistry Organic Chemistry chemistry.chemical_element Sodium metabisulfite 010402 general chemistry 01 natural sciences Sulfur 0104 chemical sciences chemistry.chemical_compound Chalcogen chemistry Transition metal Yield (chemistry) Organic chemistry Physical and Theoretical Chemistry Inert gas Selenium
Zdroj:	European Journal of Organic Chemistry. 2017:3830-3836
ISSN:	1434-193X
DOI:	10.1002/ejoc.201700648
Popis:	Herein is reported the first decarboxylative oxidation of α-keto acids promoted by sodium metabisulfite (Na2S2O5) to obtain 2-substituted benzothiazoles and benzoselenazoles. Diaryl disulfides and diselenides were used as chalcogen sources and the desired products were obtained in moderate to excellent yields. This protocol does not require inert atmosphere, transition metals or drastic reaction conditions and CO2 is released as an environmental benign co-product. The presence of Na2S2O5 was essential to guarantee the reaction completion and maximum yield of products.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1f7a6db365145da57be1dfd25b8ca431 https://doi.org/10.1002/ejoc.201700648 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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