Insulin content and arterial pressure in obese women

Autor:	M. M. Ginzburg, M. М. Гинзбург, G. S. Kozupitsa, O. V. Sergeyev
Rok vydání:	1996
Předmět:	medicine.medical_specialty business.industry Endocrinology Diabetes and Metabolism Insulin medicine.medical_treatment Diastole medicine.disease Obesity Pathogenesis Blood pressure Insulin resistance Endocrinology Basal (medicine) Internal medicine medicine business Hyperinsulinism
Zdroj:	Problems of Endocrinology. 42:17-19
ISSN:	2308-1430 0375-9660
DOI:	10.14341/probl12067
Popis:	The pathogenesis of hypertension developing in obesity is still to be studied. Hyperinsulinism and insulin resistance are believed to contribute to it. A relationship between the levels of basal and glucose-stimulated immunoreactive insulin (IRI) and arterial pressure (AP) has been studied in 36 women aged 18 to 37 suffering from obesity of the first-fourth degrees. Basal IRI level was appreciably increased and directly correlating with systolic and diastolic AP, but not related to body weight excess. AP directly depended on the degree of obesity and disease standing, but not on patient's age. These data permit us to conclude that insulin contributes to the pathogenesis of hypertension in obese women, but further studies are needed to elucidate the type and mechanisms of this contribution.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1f789cb278fbb7e73b0f7e26cced8366 https://doi.org/10.14341/probl12067 Zobrazit plný text záznamu