The Ovary as a Neuroendocrine Organ
| Autor: | Wolfgang Wuttke, Hubertus Jarry, M. Dietrich, B. Hinney, S. Maas, A.T. Teichmann, Walther Kuhn, L. Pitzel, E. Dietrich, A. Einspanier |
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| Rok vydání: | 1989 |
| Předmět: |
endocrine system
0303 health sciences medicine.medical_specialty Vasopressin Granulosa cell Vasoactive intestinal peptide 030209 endocrinology & metabolism Ovary Biology 03 medical and health sciences Paracrine signalling 0302 clinical medicine medicine.anatomical_structure Endocrinology Oxytocin Internal medicine medicine Autocrine signalling Corpus luteum hormones hormone substitutes and hormone antagonists 030304 developmental biology medicine.drug |
| Zdroj: | The Menstrual Cycle and Its Disorders ISBN: 9783540509752 |
| Popis: | The ovary of many mammalian species has been shown to produce not only steroids but also a number of regulatory peptides. Some of these peptides, like inhibin (Ying 1988), have extra ovarian functions whereas others, like oxytocin (Wathes and Swann 1982), vasopressin (Clements and Funder 1986), and Vasoactive intestinal peptide (VIP; Gozes and Tsafriri 1986; Ahmed et al. 1986) exert their function within the ovary. Hence, they act in either a para- or autocrine fashion. The messenger RNAs (mRNAs) for some of the above-mentioned peptides have been demonstrated in ovarian extracts in a number of species (Gozes and Tsafriri 1986; Jones and Flint 1988; Fuller et al. 1985; Einspanier et al. 1986). Although species differences exist in the amount of peptides produced by the different ovarian compartments, the fundamental functions of these regulatory peptides appear to be the same. Thus, oxytocin, the best-explored peptide with paracrine action in the ovary, inhibits progesterone release from cultured luteal cells from all species tested so far, including the human (Pitzel et al. 1988). |
| Databáze: | OpenAIRE |
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