| Autor: |
Anatoly Romanyuk Romanyuk, Antonina Politun, Yevhen Kuzenko |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Journal of Stomatology. 69:674-679 |
| ISSN: |
2299-551X |
| DOI: |
10.5604/00114553.1230588 |
| Popis: |
Aim of the study. To investigate the expression of CD68 and HSP90AA1 in periodontal inflammation. Methods. A total of twenty-seven patients (giant-cell epulis) and thirty patients (acute and chronic inflammations) have been examined for expression of CD68 and HSP90AA1 by hematoxylin – eosin and immunohistochemistry. Results. Strong giant-cell positivity for CD68 was observed in 100% of patients whereas only 85.31% of giant-cell was positive for HSP90AA1 (p lower than 0.05). Strong macrophage immunoreactivity for CD68 was figured in acute 23.2±1.3%, and in chronic 83.1±5.6% (p lower than 0.05) inflammation. Immunoreactivity for HSP90AA1 was fixed in acute and chronic inflammation 98.2±1.79%. Conclusion. Inflammatory macrophages are a group of cells with protective functions, macrophages being more set up in chronic inflammation. Central giant cell epulis is the multinucleated macrophages, formed as a result of chronic inflammation. Population of macrophages resulted in bone resorption. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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