ChemInform Abstract: Significant Counterion Effect of the In(III)-Pybox Complex in Highly Enantioselective Carbonyl-ene Reactions of Ethyl Glyoxylate
Autor: | Teguh‐Budiono W. Tjan, Junfeng Zhao, Teck-Peng Loh |
---|---|
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 42 |
ISSN: | 0931-7597 |
Popis: | A highly efficient enantioselective carbonyl-ene reaction of ethyl glyoxylate catalyzed by an In(III)–pybox complex, which is designed based on the counterion effect, is reported. Reactions of both aliphatic and aromatic 1,1-disubstituted olefins proceed smoothly to give enantioenriched homoallylic alcohols with excellent yields and enantioselectivities. In addition, electron-withdrawing as well as donating groups on the phenyl ring of α-methyl styrenes are tolerated in this reaction. |
Databáze: | OpenAIRE |
Externí odkaz: |