Standard Molar Enthalpies of Formation and Thermal Stabilities of Artemisinin and Its Two Derivatives: Artemether and Artesunate

Autor:	Yi Liu, Jia-Xin Dong, Zu-De Qi, Zhong-Hai Zhang
Rok vydání:	2007
Předmět:	General Chemical Engineering chemistry.chemical_element General Chemistry Calorimetry Oxygen Standard enthalpy of formation chemistry.chemical_compound chemistry Artesunate medicine Organic chemistry Thermal stability Heat of combustion Artemether Thermal analysis medicine.drug Nuclear chemistry
Zdroj:	Journal of Chemical & Engineering Data. 52:1045-1049
ISSN:	1520-5134 0021-9568
DOI:	10.1021/je7000039
Popis:	The constant-volume energy of combustion of crystalline artemisinin and its two derivatives, artemether and artesunate, in oxygen at T = 298.15 K was determined to be {−(7546.53 ± 3.24), −(7582.28 ± 3.09), and −(8150.75 ± 4.24)} kJ·mol-1 using combustion calorimetry, respectively. The derived standard molar enthalpies of formation of the three compounds in crystalline states at T = 298.15 K were {−(1492.81 ± 7.62), −(2419.75 ± 7.52), and −(3320.12 ± 9.90)} kJ·mol-1, respectively. The thermal stabilities of the three compounds were also investigated by thermal analysis combined with an FT-IR method.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1f3ed22ce461f865fbbe74ec1b43b49f https://doi.org/10.1021/je7000039 Zobrazit plný text záznamu