SARS-CoV-2 seroprevalence in workers from a Colombian University Hospital
| Autor: | K Moreno-Medina, L D Sáenz Pérez, J C Villar, E Váquiro Herrera, J E Pérez Franco, F A Varón-Vega, R Guanes Cortés, A Steevens Gualdrón, M S Sarmiento Becerra |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Occupational Medicine. 73:128-132 |
| ISSN: | 1471-8405 0962-7480 |
| Popis: | Background Antibody (Ab) tests for SARS-CoV-2 virus allows for the estimation of incidence, level of exposure and duration of immunity acquired by a previous infection. In health workers, the hospital setting might convey a greater risk of infection. Aims To describe the frequency of immunoglobulin G (IgG) Abs (IgG-Abs) to the SARS-CoV-2 virus among workers at a third-level university hospital in Colombia. Methods In this cross-sectional study, we included medical and non-medical personnel with at least one real-time polymerase chain reaction (RT–PCR)/antigen test between March 2020 and March 2021. In April 2021, an IgG-Ab test against SARS-CoV-2 was conducted for all participants and replicated 2 weeks later in a random sample (10%). The frequency of IgG-Abs is presented based on status (positive/negative) and time elapsed since RT–PCR/antigen test (6 months). Results We included 1021 workers (80% women, median age 34 years (interquartile range 28–42), 73% medical personnel, 23% with previous positive RT–PCR/antigen). The overall seroprevalence was 35% (95% CI 31.6–37.4, 35% in medical and 33% in non-medical personnel). For those with a previous positive RT–PCR/antigen test, the seroprevalence was 90% (6 months). In participants with a previous negative RT–PCR/antigen test, the seroprevalence was 17% (6 months). Conclusions High IgG-Ab positivity was found in hospital personnel, regardless of work activities. The prevalence of detectable Abs differed by previous RT–PCR/antigen status and time elapsed since the diagnostic test. |
| Databáze: | OpenAIRE |
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