Clinical and karyotypical characteristics of the Shereshevsky-Turner syndrome

Autor:	S. I. Kozlova, L. A. Tarskaya, R. S. Patyutko, V. I. Trubnikov, E. P. Kasatkina, A. N. Prytkov
Rok vydání:	1996
Předmět:	Pediatrics medicine.medical_specialty business.industry Endocrinology Diabetes and Metabolism Turner syndrome Medicine business medicine.disease
Zdroj:	Problems of Endocrinology. 42:22-24
ISSN:	2308-1430 0375-9660
Popis:	The incidence of 18 phenotypical signs was analyzed in 82 patients with the Shereshevvky-Turner syndrome. The minimal diagnostic signs occurring with at least 50% incidence have been singled out. Comparative analysis of the distribution of clinical signs in groups with different variants of karyotype disorders showed that the group of patients with the mosaic karyotype (45,X/40,XX) was the least loaded with pathological signs. Groups with karyotype 48,X and structural disorders are similar in the distribution of phenotypical signs. Multidimensional statistical cluster analysis of the matrix of summary phenotypical distances was carried out and a cluster singled out which permitted unification of 4 groups of patients with different karyotype disorders. The results are compared with published data of molecular cytogenetic studies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1f33311b4dcb583e12f965c48d5f5773 https://doi.org/10.14341/probl12038 Zobrazit plný text záznamu