A Pseudoautosomal Boundary-Like Element Adjacent to theSSAVILocus at 18q21

Autor: Thomas Werner, Ruth Brack-Werner, Jürgen H. Blusch
Rok vydání: 1999
Předmět:
Zdroj: DNA Sequence. 10:115-119
ISSN: 1042-5179
DOI: 10.3109/10425179909008428
Popis: Pseudoautosomal boundary-like (PABL) elements have been found at transition sites between genomic regions with different GC-contents. A new PAB related sequence was found immediately adjacent to the S71 provirus on human chromosome 18q21.1–2 (officially designated the SSAVZ locus). The S71 PABL element was full-length as defined by comparison with elements identified at the pseudoautosoma1 boundaries of the sex chromosomes and in the MHC region. The d'-ends of all PABL elements showed significant homology to functional CpG-islands, indicating that this similarity is a new common feature of PABL elements.
Databáze: OpenAIRE