Informational Shocks, Off-Label Prescribing, and the Effects of Physician Detailing
Autor: | Bradley Shapiro |
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Rok vydání: | 2018 |
Předmět: |
Actuarial science
Scrutiny Sales force business.industry Strategy and Management media_common.quotation_subject 05 social sciences Management Science and Operations Research Off-label use Promotion (rank) 0502 economics and business 050211 marketing 050207 economics Medical prescription Antipsychotic drug business Pharmaceutical industry media_common |
Zdroj: | Management Science. 64:5925-5945 |
ISSN: | 1526-5501 0025-1909 |
Popis: | The relationship between pharmaceutical detailing and prescriptions for non-FDA-approved (off-label) use has been the subject of regulatory scrutiny, with more than $12 billion in regulatory settlements for off-label promotion since 2004. Using the case of AstraZeneca’s antipsychotic drug, Seroquel, I study the extent to which off-label prescriptions are caused by detailing. Using a physician panel that connects detailing exposure to medical charts, I exploit within-physician variation to identify detailing effects. I find the effect of detailing on off-label prescriptions is small in both absolute and relative terms. Detailing on net tilts the prescribing distribution toward on-label. This paper was accepted by Eric Anderson, marketing. |
Databáze: | OpenAIRE |
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