Ghrelin and adiponectin levels in colostrum, cord blood and maternal serum
| Autor: | Recep Sutcu, Bumin Dündar, Gokhan Cesur, Nihal Olgaç Dündar, Fehmi Ozguner, Nigar Yilmaz |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Adiponectin business.industry animal diseases food and beverages Breast milk Anthropometry Total Ghrelin fluids and secretions Endocrinology Cord blood Internal medicine Pediatrics Perinatology and Child Health medicine Colostrum Ghrelin business Body mass index reproductive and urinary physiology hormones hormone substitutes and hormone antagonists |
| Zdroj: | Pediatrics International. 52:622-625 |
| ISSN: | 1328-8067 |
| Popis: | Background: Ghrelin and adiponectin, which are considered to take part in the regulation of energy metabolism, have been found in breast milk and cord blood. The aims of this study were to determine ghrelin and adiponectin levels in colostrum, cord blood and maternal serum and to investigate the correlations between colostrum and cord blood levels of these peptides and the anthropometry of newborn infants and their mothers. Methods: Total ghrelin (TGHR), free ghrelin (FGHR) and adiponectin levels were studied in colostrum and the serum samples of 25 healthy lactating women and the cord blood of their healthy full-term infants. Results: No significant differences could be found among TGHR and adiponectin levels in colostrum, cord blood and maternal serum. The median FGHR level in colostrum was significantly higher than that of maternal serum and cord blood. The colostrum TGHR was negatively correlated with body mass index (BMI) and weight of the infants at birth. TGHR and FGHR levels in colostrum were found to be positively correlated with those of maternal TGHR and FGHR concentrations, respectively. Adiponectin levels in colostrum were not correlated with BMI or birthweight of the infants or BMI of the mothers. Conclusion: These findings suggest that the source of ghrelin in breast milk is probably both breast tissue itself and the serum of the mother. Ghrelin in colostrum seems to be related to the anthropometry of infants even at birth, unlike adiponectin. |
| Databáze: | OpenAIRE |
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