Fused polycyclic nitrogen-containing heterocycles 13. Synthesis of 6-phenyl-2-phenylimino-6H-1,3,4-thiadiazine-5-carboxylic acid and its intermolecular cyclodehydration accompanied by sulfur extrusion to form dipyrazolo[1,5-a,1′,5′d]pyrazine

Autor:	Ya. A. Levin, Igor A. Litvinov, I. Z. Nurkhametova, A. T. Gubaidullin, Vakhid A. Mamedov
Rok vydání:	2005
Předmět:	chemistry.chemical_classification Pyrazine Carboxylic acid Intermolecular force Condensation chemistry.chemical_element General Chemistry Medicinal chemistry Sulfur Hydrolysis chemistry.chemical_compound 4-Phenylthiosemicarbazide chemistry Yield (chemistry)
Zdroj:	Russian Chemical Bulletin. 54:441-444
ISSN:	1573-9171 1066-5285
DOI:	10.1007/s11172-005-0270-z
Popis:	Condensation of methyl phenylchloropyruvate with 4-phenylthiosemicarbazide proceeds as the Bose reaction to form 5-methoxycarbonyl-6-phenyl-2-phenylimino-6H-1,3,4-thiadiazine, which is hydrolyzed to give carboxylic acid. In the presence of polyphosphoric acid, the latter undergoes intermolecular cyclodehydration accompanied by sulfur extrusion to yield dipyrazolo [1,5-a,1′,5′d]pyrazine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1ee2e6b70af18f9d6ca4a618a2876ec9 https://doi.org/10.1007/s11172-005-0270-z Zobrazit plný text záznamu Full text from SpringerLink