INFLUENCE OF IMMUNIZATION WITH ANTI-INFLUENZA VACCINE ON THE COURSE AND OUTCOME OF COMMUNITY-ACQUIRED PNEUMONIA
Autor: | Svetlana V. Naryshkina, Leonid Nakhamchen, Lyudmila Kruglyakova, Lydmila Bugaeva |
---|---|
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Pulmonary and Respiratory Medicine Pediatrics medicine.medical_specialty Influenza vaccine business.industry medicine.disease Outcome (game theory) 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030228 respiratory system Community-acquired pneumonia Immunization Pediatrics Perinatology and Child Health medicine business |
Zdroj: | Bulletin physiology and pathology of respiration. 1:40-45 |
ISSN: | 1998-5029 |
DOI: | 10.12737/article_5b189c191116a5.25087824 |
Popis: | The community-acquired pneumonia (CAP) is a very widespread disease and one of frequent causes of death. The stable relation of seasonal dynamics of indicators of a case rate of CAP with incidence of acute respiratory viral infection and flu becomes perceptible. One of the modern trends of decreasing the incidence and mortality at CAP is immunization with anti-influenza vaccines. Flu immunizations are included in the National calendar of preventive immunization of the Russian Federation. According to official data of the Ministry of Health of the Amur region, in 2015, 2016 and 2017 there were vaccinated 39.7%, 45.4% and 46.2% of population, respectively. CAP case rate in the group immunized with anti-influenza vaccine and in the group not immunized were analyzed. The decrease of the case rate of CAP in patients immunized from flu by 2.4 times in comparison with the people who were not vaccinated from flu was revealed. Against the background of mass vaccination against flu there was a change of clinical implications of CAP: the number of people with mild forms of illness enlarged. Lethality decreased: from 179 immunized people only one patient died, whereas from 393 not immunized people 28 patients had a lethal outcome. The case rate of CAP in people of the senior age groups decreased from 32.2% in 2009-2014 till 21.7% in 2015, from 17.8% in 2016 till 15.9% in 2017. Thus, immunization against flu is followed by an essential decrease of indicators of a case rate of CAP, relief of a disease and improvement of a disease outcome. |
Databáze: | OpenAIRE |
Externí odkaz: |