Copper-Catalyzed Synthesis of β- and δ-Carbolines by Double N-Arylation of Primary Amines

Autor: Nguyen Ngoc Tuan, Hoang Le Tuan Anh, Nguyen Van Tuyen, Peter Langer, Tuan Thanh Dang, Ha Nam Do, Nguyen Minh Quan, Tran Quang Hung, Ban Van Phuc, Nguyen Quang An
Rok vydání: 2021
Předmět:
Zdroj: Synlett. 32:1004-1008
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-0040-1720461
Popis: Two efficient and practical approaches are reported for the synthesis of β- and δ-carbolines from 3,4-dibromopyridine. The synthesis is based on site-selective Cu-catalyzed double C–N coupling reactions and subsequent annulations by twofold Pd-catalyzed C–N coupling with amines.
Databáze: OpenAIRE