Genetic and gender factor affect lipid profiles of patients receiving statin treatment in the east coast region of Peninsular Malaysia

Autor: Amirul Faez Shamsudin, Nur Salwani Bakar
Rok vydání: 2022
DOI: 10.22541/au.166721405.51189611/v1
Popis: Aim: This study was conducted to evaluate the impact of genetic polymorphisms on lipid profiles of statin users. Methods: This retrospective cross-sectional study involved 229 hyperlipidaemic statin users in east coast region of Peninsular Malaysia. DNA was extracted from patients’ blood (3mL) and SNP genotyping was performed using PCR-RFLP. Lipid profiles were evaluated before and after statin administration. Multi-factorial impact on the attainment of LDL goal of
Databáze: OpenAIRE