AN OVERVIEW OF TRANSDERMAL DELIVERY SYSTEM
| Autor: | Jahnara Hameed, Anupriya Anupriya, Reshmi Jayaprakash |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pharmacology
Drug integumentary system business.industry media_common.quotation_subject Pharmaceutical Science 02 engineering and technology Penetration (firestop) 021001 nanoscience & nanotechnology 030226 pharmacology & pharmacy Dosage form Bioavailability 03 medical and health sciences First pass effect 0302 clinical medicine medicine.anatomical_structure Drug delivery Stratum corneum medicine Pharmacology (medical) 0210 nano-technology business media_common Transdermal |
| Zdroj: | Asian Journal of Pharmaceutical and Clinical Research. 10:36 |
| ISSN: | 2455-3891 0974-2441 |
| DOI: | 10.22159/ajpcr.2017.v10i10.19909 |
| Popis: | Recently, most widely using conventional dosage form such as tablet, capsules, and injections but due to some case we are preferable to choose transdermal drug delivery system (TDDS) because conventional oral dosage form undergo first pass metabolism. In TDDS, skin is the effective medium for the penetration of drug into systemic circulation. This system required very low dose for the effective result or action. One of the major disadvantages of TDDS is penetration rate is very low through the stratum corneum. Nowadays, different types of skin penetration enhancement techniques are used for increasing the penetration. These types of techniques can be also increase the bioavailability. The patients have more preferable to choose this type of drug delivery system because it has more advantages than conventional dosage form. This article is discuses about the anatomy and physiology of skin and its drug penetration capacity, polymers used in transdermal drug delivery and different types of TDDS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|