| Autor: |
Ulrich G. Oppel, Eckhard Salzsieder, Uwe Fischer |
| Rok vydání: |
2003 |
| Předmět: |
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| Zdroj: |
IFAC Proceedings Volumes. 36:57-61 |
| ISSN: |
1474-6670 |
| DOI: |
10.1016/s1474-6670(17)33472-9 |
| Popis: |
Worldwide nearly 150 million people are suffering from diabetes mellitus: approximately 90 to 95 % of them, i.e. 135 to 142 million are type-2 diabetic patients exhibiting the most important endogenous cardiovascular risk condition. The development of type-2 diabetes is a discontinuous process, featuring interactions between insulin resistance and insulin secretion. In a given case, it has - until now - been impossible neither to predict nor to establish retrospectively whether one of these latter items might have been the primary event or be dominant in the progression of type-2 diabetes. Therefore it is the aim of this study to assess in a given person the developmental stage along the pathway leading towards type-2 diabetes and to quantify the risk of worsening. The underlying rationale is based upon the hypothesis that the pathogenesis of type-2 diabetes can be modelled mathematically and simulated and thereby be predicted for purposeful intervention to a certain extent. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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