Novel Quinidine-Derived Organocatalysts for the Asymmetric Substitutions of O-Boc-Protected Morita-Baylis-Hillman Adducts

Autor: Cheng-Kui Pei, Xiu-Chun Zhang, Min Shi
Rok vydání: 2011
Předmět:
Zdroj: European Journal of Organic Chemistry. 2011:4479-4484
ISSN: 1434-193X
DOI: 10.1002/ejoc.201100501
Popis: A series of novel quinidine-derived organocatalysts was synthesized and utilized for the asymmetric substitution of O-Boc-protected Morita–Baylis–Hillman adducts with various carbamates and tosylcarbamates, affording the corresponding products in good to high yields (up to 91 % yield) with moderate to high ee values (up to 96 % ee) under mild conditions.
Databáze: OpenAIRE