2-(2?-naphthyl)-2-aminoproptonic acid and its pyrimidine derivatives Part 2

Autor: V. M. Rodionov, B. L. Kurtev
Rok vydání: 1952
Předmět:
Zdroj: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 1:285-291
ISSN: 1573-9171
0568-5230
DOI: 10.1007/bf01170505
Popis: 1. β-Ureido-β-(β-naphthyl)-propionic acid,β-(ω-phenylureido)-β-(β-naphthyl)-propionic acid, andβ-(N1-methylureido)-β-(β-nepthyl)propionic acid have been prepared, and have been converted into the corresponding 2,4-dioxo-hexahydropyrimidine derivatives 6-(β-naphthyl)-dihydrouracil, 3-phenyl-6-(β-naphthyl)-dihydrouracil, and 6-(β-nappthyl)-1-methyl-dihydrouracil. 2. Its amide was formed as a by-product of preparation ofβ-ureido-β-(β-napthyl)-propionic acid, and was also synthesized fromβ-amino-β-(β-napthyl)-propionic acid and sodium cyanate. 3. β-Ureido-β-(β-naphtyhl)-propionamide undergoes cyclization when heated. 4. Methyl-β-(ω-phenylureido)-β-(β-napthyl)-propionate has been prepared. 5. 2-Thio-6-(β-napthyl)-dihydrouracil,β-guanidino-β-(β-napthyl)-propionic acid, and 4-oxo-β-(β-naphthyl)-2-methyl-3,4,5,6-tetrahydropyrimidine have been synthesized.
Databáze: OpenAIRE
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