Cytological study of early embryonic mortality in laboratory mice

Autor: Kh. Kh. Semenov, A. M. Malashenko
Rok vydání: 1975
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 80:1249-1251
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00833176
Popis: Early embryogenesis was studied cytologicaly in laboratory mice. Preimplantation embryonic mortality among DBA/2JY, C57BL/6JY, and 101/HY mice and among CBWA females crossed with B6 males did not exceed 4–6%. An exception was the AKR/JY mice, with a preimplantation mortality of 29.6%. Investigation of the nature of chemically induced dominant lethals showed that the arrest of cleavage and death of the embryos were caused by gross structural changes in the chromosomes.
Databáze: OpenAIRE