The effect of dietary morfamquat on mitochondrial function in rat kidney

Autor: J.A. Poat, D. Morris, Kenneth A. Munday
Rok vydání: 1972
Předmět:
Zdroj: International Journal of Biochemistry. 3:378-382
ISSN: 0020-711X
DOI: 10.1016/0020-711x(72)90087-0
Popis: 1. 1. Mitochondria, prepared from the medullary-papillary region of kidneys from male adult rats which had been fed with a low (0.015 per cent) dietary concentration of morfamquat dichloride for 18–20 weeks, were functionally examined. 2. 2. Respiratory control indices, P : O ratios, and respiration rates were significantly lower than the corresponding values for control animals. 3. 3. The biochemical lesion was restricted to the medullary-papillary zone, the cortical mitochondria having normal properties.
Databáze: OpenAIRE