Role of Diffusion Weighted Magentic Resonance Imaging in Evaluation of Hepatocellular Carcinoma Post Chemoembolization

Autor: Atef Hammad Teama, Hanan Ahmad Nagy Mohammed Saleh, Ahmed Hassan Ali Moustafa
Rok vydání: 2022
Předmět:
Zdroj: Journal of Advances in Medicine and Medical Research. :65-75
ISSN: 2456-8899
DOI: 10.9734/jammr/2022/v34i1031355
Popis: Background: Hepatocellular carcinoma (HCC) is the fifth most common type of cancer in the world and the third most prevalent frequent death reason in patients who suffers from malignant tumors. The apparent diffusion coefficient (ADC) is a method for measurement of the water movement within tissues. Tumors that are viable have a high cellularity, and the cells' membranes are intact which water molecules' mobility is restricted, leading to a small ADC. But from the other hand, necrosis increases the permeability of the cell of the membrane, permitting water molecules to circulate freely and resulting in an elevation in the ADC's relative value. This study aimed to describe the use of diffusion weighted MRI to evaluate hepatocellular carcinoma in the setting of trans-arterial chemoembolization (TACE). Methods: This study was carried out on 30 patient (males: 22, eight females) aged 42 to 75 years with biopsy-proven HCC, candidate for trans arterial hepatic chemoembolization as a plan of treatment. They were referred from Oncology Department to MRI unit in radiology department over a period of 1 year starting in June 2018 to June 2019. Results: According to diffusion weighted Imaging (DWIs) and ADC values, there were 4 TP (13.33%), 22 TN (73.33%), 2 FP (6.66%) and 2 FN (6.66%) studies. The P-value by Fisher’s Exact was
Databáze: OpenAIRE