Antimicrobial efficacy of a hemilabile Pt(ii )–NHC compound against drug-resistant S. aureus and Enterococcus
| Autor: | Mandeep Kaur, Ritesh Thakare, Arindom Bhattacherya, Prem Anand Murugan, Grace Kaul, Manjulika Shukla, Alok Kr. Singh, Saravanan Matheshwaran, Sidharth Chopra, Jitendra K. Bera |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Dalton Transactions. 52:1876-1884 |
| ISSN: | 1477-9234 1477-9226 |
| DOI: | 10.1039/d2dt03365h |
| Popis: | A newly designed Pt(ii)–NHC complex shows potent activity against the Gram-positive S. aureus pathogen. Further investigation reveals biofilm inhibition, in vivo activity inside mammalian cells, and combinatorial antimicrobial activity with FDA-approved drugs. |
| Databáze: | OpenAIRE |
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