Development of Fe3O4/reduced graphene oxide nanocomposite-based dispersive solid-phase extraction for the quantification of five steroid hormones

Autor:	Neşe Ular Çağatay, Murat Emrah Maviş, Sezin Erarpat, Sezgin Bakırdere
Rok vydání:	2023
Předmět:	Medical Laboratory Technology Clinical Biochemistry General Medicine General Pharmacology Toxicology and Pharmaceutics Analytical Chemistry
Zdroj:	Bioanalysis.
ISSN:	1757-6199 1757-6180
DOI:	10.4155/bio-2023-0025
Popis:	Aim: An accurate and sensitive analytical method was proposed to detect some steroid hormones in biological samples. Materials & methods: An Fe3O4/reduced graphene oxide nanocomposite-based dispersive solid-phase extraction was developed for the effective and simple preconcentration of steroid hormones from human serum samples. Results & conclusion: The nanocomposite was firstly used as adsorbent to simultaneously extract the selected hormones. Limit of detection values for the selected hormones were calculated between 5.5 and 39.2 ng/kg (mass based). An artificial serum sample was used to test the applicability and accuracy of the developed method; percentage recovery results obtained from two different spiked concentrations were found to be in the range of 80.5–99.9%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1e1df50e55b3142402b99a869c8efd6d https://doi.org/10.4155/bio-2023-0025 Zobrazit plný text záznamu