Palladium-Catalyzed Cross-Coupling of Alkynyl Carboxylic Acids with Isocyanides: Solvent-Controlled Selective Synthesis of 5-Iminofuranones and 5-Iminopyrrolones

Autor: Huanfeng Jiang, Jiawei Li, Wanqing Wu, Weigao Hu, Hai-Yang Liu, Zun Li
Rok vydání: 2017
Předmět:
Zdroj: Advanced Synthesis & Catalysis. 359:3509-3514
ISSN: 1615-4150
Popis: A novel palladium-catalyzed cyclization of alkynyl carboxylic acids with isocyanides has been successfully developed herein. The corresponding 5-iminofuranone or 5-iminopyrrolone derivatives were constructed in moderate to good yields which were well controlled by the solvents. These reactions proceed under simple and mild reaction conditions with high efficiency, and feature a wide substrate scope, readily available starting materials and easy operation.
Databáze: OpenAIRE
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