Efficacité de l’association de sparfloxacine et d’éthambutol dans un cas de tuberculome cérébral

Autor:	Boukriche Y, B Fantin, Zarrouk, C Masson
Rok vydání:	2002
Předmět:	medicine.medical_specialty business.industry Isoniazid Gastroenterology Pyrazinamide bacterial infections and mycoses Regimen Sparfloxacin Cerebral tuberculosis Internal medicine Internal Medicine medicine Tuberculoma business Rifampicin Ethambutol medicine.drug
Zdroj:	La Revue de Médecine Interne. 23:92-96
ISSN:	0248-8663
DOI:	10.1016/s0248-8663(01)00519-7
Popis:	INTRODUCTION Treatment of cerebral tuberculomas demands the combination of rifampicin, isoniazid, pyrazinamide and ethambutol. The place of fluoroquinolones remains to be defined. EXEGESIS A 36-year-old woman presented with a cerebral tuberculoma. Treatment with an antituberculous quadritherapy regimen was begun, but because of serious side effects, isoniazid and rifampicin weren't withdrawn during the fourth month. Sparfloxacin and ethambutol biotherapy was then started and continued for 12 months, which led to the disappearance of the cerebral lesion. CONCLUSION Our observation proves that sparfloxacin is an alternative for cerebral tuberculoma treatment in case of intolerance or resistance to first-line antituberculosis drugs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1de70b69cf0505cc9c546fe56e003c92 https://doi.org/10.1016/s0248-8663(01)00519-7 Zobrazit plný text záznamu Full Text from ScienceDirect