Topische Dexamethason-Therapie
| Autor: | Er-Ping Zhang, A. Müller, Friedrich Hoffmann |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Pathology
medicine.medical_specialty Frozen section procedure genetic structures medicine.drug_class business.industry Antigen presentation eye diseases Transplantation Ophthalmology medicine.anatomical_structure Stroma Cornea medicine Corticosteroid sense organs business Antigen-presenting cell Dexamethasone medicine.drug |
| Zdroj: | Der Ophthalmologe. 100:310-313 |
| ISSN: | 1433-0423 0941-293X |
| DOI: | 10.1007/s00347-002-0728-4 |
| Popis: | OBJECTIVE To determine the influence of dexamethasone treatment on APCs and the time of graft survival of MHC-disparate grafts. METHODS Flatmounts of the ocular surface prepared with EDTA and tangential frozen sections of the remaining corneal stroma from untreated eyes of normal mice (n=6) and from eyes treated for 7 days with dexamethasone ( n=6) were immunohistologically examined for content of F4/80+ and MHC II+ cells.Furthermore, corneas of C(3)H mice without and with 7-day dexamethasone eye drop treatment (n=8) were grafted into BALB/c mice receiving the same treatment. RESULTS The number of positive cells within the epithelial flatmounts showed a dramatic reduction in the dexamethasone-pretreated group (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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