Quantitative disease resistance to the bacterial pathogenXanthomonas campestrisinvolves an Arabidopsis immune receptor pair and a gene of unknown function
| Autor: | Marilyne Debieu, Carine Huard-Chauveau, Anne Genissel, Fabrice Roux, Dominique Roby |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Genetics Candidate gene biology Mutant Soil Science Plant Science Immune receptor Plant disease resistance biology.organism_classification Xanthomonas campestris 03 medical and health sciences 030104 developmental biology Arabidopsis Arabidopsis thaliana Agronomy and Crop Science Molecular Biology Gene |
| Zdroj: | Molecular Plant Pathology. 17:510-520 |
| ISSN: | 1464-6722 |
| Popis: | Summary Although quantitative disease resistance (QDR) is a durable and broad-spectrum form of resistance in plants, the identification of the genes underlying QDR is still in its infancy. RKS1 (Resistance related KinaSe1) has been reported recently to confer QDR in Arabidopsis thaliana to most but not all races of the bacterial pathogen Xanthomonas campestris pv. campestris (Xcc). We therefore explored the genetic bases of QDR in A. thaliana to diverse races of X. campestris (Xc). A nested genome-wide association mapping approach was used to finely map the genomic regions associated with QDR to Xcc12824 (race 2) and XccCFBP6943 (race 6). To identify the gene(s) implicated in QDR, insertional mutants (T-DNA) were selected for the candidate genes and phenotyped in response to Xc. We identified two major QTLs that confer resistance specifically to Xcc12824 and XccCFBP6943. Although QDR to Xcc12824 is conferred by At5g22540 encoding for a protein of unknown function, QDR to XccCFBP6943 involves the well-known immune receptor pair RRS1/RPS4. In addition to RKS1, this study reveals that three genes are involved in resistance to Xc with strikingly different ranges of specificity, suggesting that QDR to Xc involves a complex network integrating multiple response pathways triggered by distinct pathogen molecular determinants. |
| Databáze: | OpenAIRE |
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