ChemInform Abstract: A Transaminative Synthesis of 9-Amino-9-fluorenecarboxylic Acid Esters

Autor:	Mark T. DuPriest, Raymond E. Conrow, Daniel Kuzmich
Rok vydání:	2010
Předmět:	Hydrolysis chemistry.chemical_compound Chemistry Methyl chloroformate 9-amino-9-fluorenecarboxylic acid Imine General Medicine Medicinal chemistry
Zdroj:	ChemInform. 22
ISSN:	0931-7597
DOI:	10.1002/chin.199123130
Popis:	The benzyl imines of several fluorenones were treated with base, followed by methyl chloroformate, to introduce the carbomethoxy group at the 9-fluorenyl position. Imine hydrolysis afforded the title compounds. The reaction was readily conducted on a 30-g scale.
Databáze:	OpenAIRE
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