Utilisation of food industry by-products in the production of oxytetracycline by Streptomyces rimosus 93060

Autor: Ahmed I. El-Diwany, Abou-Zeid A. Abou-Zeid, Hassan M. Salem, Hossam El-Deen Shaker
Rok vydání: 1980
Předmět:
Zdroj: Agricultural Wastes. 2:293-301
ISSN: 0141-4607
DOI: 10.1016/0141-4607(80)90006-2
Popis: Different carbon sources were utilised in the biosynthesis of oxytetracycline by S. rimosus 93060. Glucose was the best carbon source for antibiotic production in a medium with peptone as the nitrogen source. Two agricultural wastes were used as cheap partial replacements for glucose. The first was Egyptian black-strap molasses. The influence of Egyptian black-strap molasses obtained from different sugar cane manufacturers was tested. Abou-Korkas molasses was the best for the production of oxytetracycline. Potassium ferrocyanide, EDTA and methylene blue were used in the chelation or reduction of inorganic salts present in Abou-Korkas molasses. These materials did not give high titres of oxytetracycline. The suitability of Abou-Korkas molasses was due to its micronutrients. A second substrate tested for antibiotic production was the freeze-dried olive water obtained from the pressing and separation of olive oil. The chemical composition of olive water was investigated. Olive water alone was a poor substrate for antibiotic production, but with glucose it was as effective as molasses.
Databáze: OpenAIRE