Chlorinated dioxin, dibenzofuran, coplanar, mono-ortho, and di-ortho substituted PCB congener levels in blood and semen of Michigan Vietnam veterans compared with levels in Vietnamese exposed to Agent Orange

Autor: Kathy Boggess, Harry McGee, Arnold Schecter, J.S. Stanley
Rok vydání: 1993
Předmět:
Zdroj: Chemosphere. 27:241-252
ISSN: 0045-6535
DOI: 10.1016/0045-6535(93)90298-j
Popis: In the present study, conducted in 1991 and 1992, fifty Vietnam veterans from Michigan volunteered to have their blood analyzed for chlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). Seventeen of these veterans also contributed semen which was analyzed in three composite samples. Six of fifty Michigan veterans exhibited elevated TCDD blood levels ranging from 20.4 to 131 parts per trillion (ppt). The remaining forty-four had TCDD levels ranging from not detected to 8.3 ppt, with a mean level of 4.1 ppt lipid. Semen TCDD levels ranged from 0.00178 to 0.0034 ppt wet weight in the three composite samples. The veterans had total coplanar, mono- and di-ortho PCBs blood lipid levels ranging from 49,900 to 628,000 ppt, lipid. The PCB levels in these fifty veterans do not reflect exposure in Vietnam but do indicate that total dioxin-like toxicity in Americans, including Vietnam veterans, is greater than that from dioxins and dibenzofurans alone.
Databáze: OpenAIRE