Efficacy of vonoprazan-based second-lineHelicobacter pylorieradication therapy in patients for whom vonoprazan-based first-line treatment failed

Autor: Kouji Toyoda, Yuumi Kusano, Toshikuni Suda, Yasumi Katayama, Shogo Adachi, Itsuo Terauchi, Morio Takahashi, Shigeki Oka, Masaya Tamano
Rok vydání: 2016
Předmět:
Zdroj: Gut. 66:752-753
ISSN: 1468-3288
0017-5749
DOI: 10.1136/gutjnl-2016-312028
Popis: We read with great interest the article by Murakami et al ,1 who performed a randomised, double-blinded study of vonoprazan-based Helicobacter pylori ( H. pylori ) eradication therapy. They showed high success rates for vonoprazan-based first-line and second-line H. pylori treatments, with eradication rates of 92.6% and 98%, respectively. However, the study populations of second-line therapy included patients for whom both lansoprazole-based and vonoprazan-based first-line treatments failed, and those for whom vonoprazan-based first-line therapy failed numbered only 14. In terms of second-line therapy, we think that the eradication rate in patients for whom vonoprazan-based first-line therapy failed is more important. We conducted …
Databáze: OpenAIRE