Evolución de cirrosis biliar primaria a síndrome de solapamiento con hepatitis autoinmune en paciente con hepatitis B crónica

Autor: Isabel Marquina Ibáñez, José Carlos Erdozaín Sosa, Óscar Núñez Martínez, Elena Ruiz Bravo-Burguillos, Alfonso Encinas Sotillos
Rok vydání: 2013
Předmět:
Zdroj: Gastroenterología y Hepatología. 36:382-387
ISSN: 0210-5705
DOI: 10.1016/j.gastrohep.2012.07.007
Popis: We describe the case of a female patient with a previous diagnosis of primary biliary cirrhosis (PBC) and chronic hepatitis B in inactive phase who developed increased transaminase levels with no evidence of hepatitis B virus reactivation while receiving ursodeoxycholic acid treatment. A liver biopsy showed changes compatible with overlapping autoimmune hepatitis (AIH). Budesonide treatment achieved normalization of transaminase levels. We provide a review of PBC and AIH overlap syndrome and discuss the particular features of this case that led us to this diagnosis, as well as the treatment provided.
Databáze: OpenAIRE