Application of core–shell PEGylated CdS/Cd(OH)2 quantum dots as biolabels of Trypanosoma cruzi parasites
| Autor: | F.D. de Menezes, Adriana Fontes, C.R. Chaves, Beate S. Santos, André Galembeck, C. L. Cesar, Regina Celia Bressan Queiroz de Figueiredo, Patricia M. A. Farias, Ricardo de C. Ferreira |
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| Rok vydání: | 2008 |
| Předmět: |
biology
Stereochemistry Chemistry Confocal General Physics and Astronomy Kinetoplastida Surfaces and Interfaces General Chemistry Condensed Matter Physics biology.organism_classification Endocytosis Fluorescence Surfaces Coatings and Films law.invention Quantum dot Confocal microscopy law parasitic diseases Fluorescence microscope Biophysics Trypanosoma cruzi |
| Zdroj: | Applied Surface Science. 255:728-730 |
| ISSN: | 0169-4332 |
| DOI: | 10.1016/j.apsusc.2008.07.035 |
| Popis: | Semiconductor quantum dots are a promising class of materials in the labeling of biological systems. In the present study we show the marking pattern of Trypanosoma cruzi (T. cruzi) live parasites using PEGylated CdS/Cd(OH)2 fluorescent nanocrystals. The analysis obtained by confocal fluorescence microscopy and transmission electron microscopy indicates that only the endocytic paths of parasites were labeled. The parasites were alive after the incubation with the CdS/Cd(OH)2–PEG suspension. Labeling the T. cruzi with quantum dots can help to better understand the endocytosis process and also the cellular differentiation. |
| Databáze: | OpenAIRE |
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