Treatment of Cutaneous Sarcoidosis With Chloroquine

Autor: David H. Horowitz, John A. Zic, Lloyd E. King, Carmen Arzubiaga
Rok vydání: 1991
Předmět:
Zdroj: Archives of Dermatology. 127:1034
ISSN: 0003-987X
DOI: 10.1001/archderm.1991.01680060108015
Popis: • Systemic corticosteroids may be either contraindicated or not efficacious in treating the cutaneous manifestations occurring in 20% to 35% of patients with systemic sarcoidosis. Chloroquine phosphate has been reported to be a valuable alternative therapy for cutaneous lesions of sarcoidosis. With a judiciously determined daily dosage and regular 6-month ophthalmologic follow-up examinations, the risk of developing retinopathy can be avoided, because the daily dosage rate rather than total dose accumulation determines the development of chloroquine-induced retinopathy. We reviewed the efficacy and safety of chloroquine and its role in the treatment of cutaneous sarcoidosis. ( Arch Dermatol. 1991;127:1034-1040)
Databáze: OpenAIRE