Autor: |
David H. Horowitz, John A. Zic, Lloyd E. King, Carmen Arzubiaga |
Rok vydání: |
1991 |
Předmět: |
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Zdroj: |
Archives of Dermatology. 127:1034 |
ISSN: |
0003-987X |
DOI: |
10.1001/archderm.1991.01680060108015 |
Popis: |
• Systemic corticosteroids may be either contraindicated or not efficacious in treating the cutaneous manifestations occurring in 20% to 35% of patients with systemic sarcoidosis. Chloroquine phosphate has been reported to be a valuable alternative therapy for cutaneous lesions of sarcoidosis. With a judiciously determined daily dosage and regular 6-month ophthalmologic follow-up examinations, the risk of developing retinopathy can be avoided, because the daily dosage rate rather than total dose accumulation determines the development of chloroquine-induced retinopathy. We reviewed the efficacy and safety of chloroquine and its role in the treatment of cutaneous sarcoidosis. ( Arch Dermatol. 1991;127:1034-1040) |
Databáze: |
OpenAIRE |
Externí odkaz: |
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