Synthesis, resolution and determination of energy barriers to rotation of atropisomeric, planar-chiral [n]paracyclophanes by dynamic enantioselective gas chromatography and computer simulation

Autor:	Wilfried A. König, Detlev H. Hochmuth
Rok vydání:	1999
Předmět:	Resolution (mass spectrometry) Elution Chemistry Organic Chemistry Enantioselective synthesis Rotation Catalysis Inorganic Chemistry Planar Computational chemistry Organic chemistry Gas chromatography Physical and Theoretical Chemistry Energy (signal processing)
Zdroj:	Tetrahedron: Asymmetry. 10:1089-1097
ISSN:	0957-4166
DOI:	10.1016/s0957-4166(99)00092-0
Popis:	We herein report on the synthesis of substituted carbocyclic [11]paracyclophanes, which are planar-chiral and atropisomeric. Their energy barrier to rotation was determined by dynamic enantioselective gas chromatography on selectively modified cyclodextrins as chiral stationary phases and subsequent computer simulation of the plateau-shaped elution profiles (DGC–CS). The energy barriers are compared with those of analogous dioxa[11]paracyclophanes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1d74951e5dd0f0e925bca148171b8778 https://doi.org/10.1016/s0957-4166(99)00092-0 Zobrazit plný text záznamu Full Text from ScienceDirect