| Autor: |
Adrian B. Bonner, Colin R. Martin |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
Current Psychiatry Reviews. 1:303-312 |
| ISSN: |
1573-4005 |
| DOI: |
10.2174/157340005774575136 |
| Popis: |
Alcohol dependency is a complex multi-factorial clinical presentation characterized by etiological ambiguity, poor treatment adherence and unfavorable prognosis. Recent evidence suggest considerable heterogeneity in this patient group across a number of neurological, genetic, psychological and personality parameters which relate directly to the clinical manifestation and course of this chronic condition. The current review examines contemporary cross-disciplinary research reports to present an integrated psychobiological synthesis of the main themes. The psychobiological model proposed offers a template for both clinicians and researchers to evaluate the relative contribution of key indicators to the end-point gestalt of alcohol dependency. Analysis and integration of psychobiological risk factors are illuminated within the context of sub-type identification, tailored treatment interventions and clinical outcome prediction. Implications for current psychiatric practice and the direction of future research are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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