A new approach to the synthesis of pyrido[4,3-b]indole derivatives (γ-carbolines) via cyclization of enamino dinitriles

Autor:	Alexander S. Shashkov, O. B. Smirnova, Vladimir G Granik, L. M. Alekseeva, T. V. Golovko
Rok vydání:	2008
Předmět:	Indole test chemistry.chemical_compound Phosphoryl chloride chemistry Cyclohexanone Organic chemistry General Chemistry Alkylation
Zdroj:	Russian Chemical Bulletin. 57:2410-2417
ISSN:	1573-9171 1066-5285
Popis:	Reactions of 2-dicyanomethylidene-3-ethoxymethylidene-2,3-dihydroindole with various amines afforded enamino dinitriles and the corresponding pyrido[4,3-b]indoles (γ-carbolines). 3-Amino-4-cyano-5H-pyrido[4,3-b]indole reacted with cyclohexanone to give pentacyclic 13-amino-2,3,4,12-tetrahydro-1H-benzo[b]indolo[2,3-f]-1,8-naphthyridine. Alkylation of pyrido[4,3-b]indoles with various alkylating agents was studied.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1d64bc8c13a81e0a0be133d959009633 https://doi.org/10.1007/s11172-008-0344-9 Zobrazit plný text záznamu Full text from SpringerLink