Correlation of the Secretion of Ovarian Steroids with Function of a Single Generation of Corpora Lute a in the Immature Rat1
| Autor: | Walter G. Wiest, Inoru Hashimoto |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
endocrine system
medicine.medical_specialty urogenital system media_common.quotation_subject Ovary Luteal phase Biology Endocrinology medicine.anatomical_structure Internal medicine Luteolysis medicine Ovulation cycle Luteinizing hormone Corpus luteum Ovulation hormones hormone substitutes and hormone antagonists reproductive and urinary physiology Hormone media_common |
| Zdroj: | Endocrinology. 84:873-885 |
| ISSN: | 1945-7170 0013-7227 |
| Popis: | Ovulation and luteinization have been artificially induced in prepuberal rats by the administration of 4 IU PMS. Evidence for luteal function was provided by the establishment of pseudopregnancy and the induction of deciduomata. The animal preparation has been successfully used to determine the secretory pattern of ovarian steroids during the first ovulation cycle and pseudopregnancy, to obtain quantitative data on the “functional” capacity of the first generation corpora lutea, and to relate ovarian 20α-OH-steroid dehydrogenase activityactivity to luteal function. Preovulatory secretion of progesterone has been related to the discharge of the ovulating hormone. Post-ovulatory secretion of progesterone has been correlated with luteal function. Ovarian 20α-OH-steroid dehydrogenase activity, localized biochemically in the corpora lutea, provided an index of luteolysis. Increasing enzyme activity resulted in increased 20α-OH-pregn-4-en-3-one and reduced progesterone concentrations in ovarian effluent blood a... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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