18F-6-Fluoro-l-Dopa PET/CT Imaging of Congenital Hyperinsulinism
| Autor: | Hongming Zhuang, Lisa J. States, Steven M. Hamel, Susan A. Becker, J. Christopher Davis |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Insulin medicine.medical_treatment Pet ct imaging Brain damage Hypoglycemia medicine.disease medicine.disease_cause Pancreatectomy Congenital hyperinsulinism Medicine Radiology Nuclear Medicine and imaging Radiology medicine.symptom business Hyperinsulinemic hypoglycemia Hyperinsulinism |
| Zdroj: | Journal of Nuclear Medicine. 62:51S-56S |
| ISSN: | 2159-662X 0161-5505 |
| Popis: | Congenital hyperinsulinism is characterized by persistent hypoglycemia due to inappropriate excess secretion of insulin resulting in hyperinsulinemic hypoglycemia. The clinical course varies from mild to severe, with a significant risk for brain damage. Imaging plays a valuable role in the care of infants and children with severe hypoglycemia unresponsive to medical therapy. 18F-6-fluoro-l-dopa PET/CT is the method of choice for the detection and localization of a focal lesion of hyperinsulinism. Surgical resection of a focal lesion can lead to a cure with limited pancreatectomy. This article reviews the role of 18F-6-fluoro-l-dopa PET/CT in the management of this vulnerable population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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