Successful management of multiple extrapulmonary complications associated withRhodococcus equipneumonia in a foal
| Autor: | Edwina Wilkes, Allan Kessell, Kris Hughes, Sharanne Raidal |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Blood transfusion 040301 veterinary sciences animal diseases medicine.medical_treatment 030204 cardiovascular system & hematology 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Internal medicine biology.animal Clarithromycin parasitic diseases medicine Rhodococcus equi biology Equine business.industry 04 agricultural and veterinary sciences bacterial infections and mycoses medicine.disease biology.organism_classification Haemolysis respiratory tract diseases Pneumonia Foal Immunology business Uveitis medicine.drug |
| Zdroj: | Equine Veterinary Education. 28:186-192 |
| ISSN: | 0957-7734 |
| Popis: | Summary This report describes the diagnosis and successful treatment of multiple extrapulmonary sequelae of Rhodococcus equi (R. equi) pneumonia in a 3-month-old filly. Bilateral uveitis and hyphaema, haemolytic anaemia and polysynovitis developed in this foal and were likely due to immune-mediated mechanisms. The challenges associated with diagnosis and treatments of these extrapulmonary disorders are discussed. The filly was treated initially with clarithromycin and rifampin; however, a blood transfusion and immunosuppressive therapy with dexamethasone were required due to progressive haemolysis and for treatment of uveitis and polysynovitis. Bilateral hyphaema was successfully treated with intracameral injections of a recombinant tissue plasminogen activator. The development of antimicrobial resistance in R. equi was an additional challenge encountered in the management of this case and emphasises the importance of culture and in vitro antimicrobial susceptibility testing of isolates from foals with R. equi pneumonia. Extrapulmonary disorders associated with R. equi pneumonia are likely underdiagnosed and associated with a poor prognosis. This case highlights the importance of thorough and ongoing diagnostic assessment of foals with R. equi pneumonia and demonstrates that a successful outcome can be achieved with appropriate and directed treatment. |
| Databáze: | OpenAIRE |
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