Unilateral multicystic dysplastic kidney: a combined pre- and postnatal assessment
| Autor: | N. S. Den Hollander, Titia E. Cohen-Overbeek, L. van Eijk, Juriy W. Wladimiroff, J. M. Nijman |
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| Rok vydání: | 2002 |
| Předmět: |
Polyhydramnios
Kidney medicine.medical_specialty Radiological and Ultrasound Technology business.industry Urology Multicystic dysplastic kidney Obstetrics and Gynecology Renal function Oligohydramnios Prenatal diagnosis General Medicine medicine.disease Surgery medicine.anatomical_structure Reproductive Medicine Renal pathology medicine Radiology Nuclear Medicine and imaging business Kidney disease |
| Zdroj: | Ultrasound in Obstetrics and Gynecology. 19:180-183 |
| ISSN: | 0960-7692 |
| DOI: | 10.1046/j.0960-7692.2001.00497.x |
| Popis: | Objective To review the prenatal assessment of associated renal pathology, non-renal pathology and renal biometry, fetal outcome and postnatal urological management in the presence of unilateral fetal multicystic dysplastic kidney. Methods A total of 38 singleton pregnancies with fetal unilateral multicystic dysplastic kidney was studied over a 13-year period. Prenatally, fetal biometry, including head and abdominal circumferences and largest longitudinal diameter of the affected and contralateral kidneys, was performed. The amount of amniotic fluid was assessed. Fetal karyotyping was offered in cases of contralateral renal or non-renal pathology. A MAG 3 scan and voiding cystogram was performed approximately 4 weeks after delivery to establish renal function and to exclude urinary reflux. Results Unilateral fetal multicystic dysplastic kidney was left-sided in 53% and right-sided in 47% of cases. The fetus was male in 63% and female in 37% of cases. Associated renal and non-renal pathology existed in 21% and 5% of cases, respectively. The fetal karyotype in these subsets was always normal. The longitudinal diameter of the multicystic dysplastic kidney was above the 95th centile in 87%. There was polyhydramnios in three cases and oligohydramnios in two cases. The prematurity rate was 16%. Postnatal examination revealed a non-functional multicystic kidney in 87% (33/38) of cases. Following surgical removal of the affected kidney, these infants progressed normally. Of the remaining five infants, four died because of associated anomalies and one infant developed normally without surgery. Conclusions Fetal outcome is determined by associated renal and/or non-renal structural pathology and not by the size/location of the unilateral multicystic dysplastic kidney or amniotic fluid volume. Copyright © 2002 ISUOG |
| Databáze: | OpenAIRE |
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