Determining the Antifungal Agent Clioquinol by HPLC, the Not So Pure Preparation: A Laboratory-Based Case Study for an Instrumental Analytical Chemistry Course

Autor: Peter M. Schaber, Geoffrey Hobika
Rok vydání: 2018
Předmět:
Zdroj: Journal of Chemical Education. 95:445-450
ISSN: 1938-1328
0021-9584
DOI: 10.1021/acs.jchemed.7b00750
Popis: The case study approach provides students with a better appreciation of how scientists solve problems and conduct themselves in the “real world”. When applied to the undergraduate chemistry laboratory, this approach also challenges critical thinking skills and creativity in ways “cook book” experiments very often do not. This approach provides students the opportunity to learn analytical principles in the context of relevant everyday problems, stimulate a sustaining interest, and develop higher cognitive skills and reasoning abilities. The laboratory-based case study described here combines the use of small collaborative groups and a modern instrumental technique, with application to a common consumer product. Students are required to conduct themselves as chemists would, when addressing the problem of product purity claims, and to make a determination based on their experimental results that will be used to direct future action taken by a formulation company. This case study even addresses potential lega...
Databáze: OpenAIRE