| Autor: | V. G. Konusova, G. Sh. Mchedlidze, V. Yu. Chebotarev, Simbirtsev Andrey S, B. A. Paramonov |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
business.industry
medicine.medical_treatment Therapeutic effect Biopterin Interleukin General Medicine Pharmacology General Biochemistry Genetics and Molecular Biology In vitro Peripheral blood chemistry.chemical_compound Cytokine chemistry Immunology Pine resin medicine Tumor necrosis factor alpha business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 134:151-155 |
| ISSN: | 0007-4888 |
| DOI: | 10.1023/a:1021184214627 |
| Popis: | We studied the effects of water-soluble fractions of pine resin and Biopin-10 and Biopin-20 ointments used for the therapy of burns, wounds, and purulent and inflammatory diseases on spontaneous and induced synthesis of tumor necrosis factor and interleukins 1, 2, and 8 by human peripheral blood neutrophils in vitro. These preparations contain various bioactive substances producing opposite and dose-dependent immunomodulatory effects. Our results indicate that the composition and doses of preparations should be selected to achieve the maximum therapeutic effect. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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