Synthesis, characterization and SOD-like activities of manganese-containing complexes with N,N,N′,N′-tetrakis(2′-benzimidazolyl methyl)-1,2-ethanediamine (EDTB)

Autor:	Zhan-Ru Liao, Liao-Rong Shen, He-Li Liu, Bao-Sheng Luo, Xue-Feng Zheng, Wei Zhao, Dongfeng Li
Rok vydání:	2001
Předmět:	Benzimidazole Denticity biology Superoxide Stereochemistry Ligand chemistry.chemical_element Manganese Medicinal chemistry Catalysis Inorganic Chemistry Superoxide dismutase chemistry.chemical_compound chemistry Octahedron Materials Chemistry biology.protein Physical and Theoretical Chemistry
Zdroj:	Polyhedron. 20:2813-2821
ISSN:	0277-5387
DOI:	10.1016/s0277-5387(01)00891-9
Popis:	A series of manganese-containing mononuclear and binuclear model compounds of superoxide dismutase (SOD) coordinated by a polydentate ligand N,N,N′,N′-tetrakis(2′-benzimidazolyl methyl)-1,2-ethanediamine (EDTB) have been synthesized and characterized. The SOD-like activities of these complexes have been measured by means of modified nitroblue tetrazolium (NBT) photoreduction, and the rate constants kQ of catalytic superoxide dismutation are in the range 6.96×106–2.32×107 l mol−1 s−1. In complex [Mn(EDTB)(Ac)](Ac)·C2H5OH the coordination environment around the manganese(II) ion can be described as a highly-distorted capped octahedron with an oxygen atom of the bidentate acetate ion at the capping site. This complex is the first example in which EDTB acts as a pentadentate ligand with one non-ligating benzimidazole group.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1cca92bf3c40ece47afe57a49e86429f https://doi.org/10.1016/s0277-5387(01)00891-9 Zobrazit plný text záznamu Full Text from ScienceDirect