Biodegradable radioactive implants for glaucoma filtering surgery produced by ion implantation

Autor:	M. Schubert, D. Streufert, A. Chill, K. Schlösser, S. Kiermaier, A. Pichler, Walter Assmann, A. Held, K. Schenk, I. Lanzl, H. Busch
Rok vydání:	2007
Předmět:	Nuclear and High Energy Physics Materials science Ion beam medicine.medical_treatment Brachytherapy Glaucoma medicine.disease Ion Ion implantation medicine Irradiation Implant Glaucoma filtering surgery Instrumentation Biomedical engineering
Zdroj:	Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 257:108-113
ISSN:	0168-583X
Popis:	A biodegradable, β-emitting implant has been developed and successfully tested which prevents fresh intraocular pressure increase after glaucoma filtering surgery. Ion implantation has been used to load the polymeric implants with the β-emitter 32 P. The influence of ion implantation and gamma sterilisation on degradation and 32 P-fixation behavior has been studied by ion beam and chemical analysis. Irradiation effects due to the applied ion fluence (10 15 ions/cm 2 ) and gamma dose (25 kGy) are found to be tolerable.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1cc3bb9002679055d2578cf338143883 https://doi.org/10.1016/j.nimb.2006.12.155 Zobrazit plný text záznamu Full Text from ScienceDirect